Vécuronium : interactions médicamenteuses

Vécuronium, bloquant neuromusculaire, présente 71 interactions documentées dans les notices FDA et les fiches d'information que nous indexons : 6 de niveau majeur, 41 de niveau modéré, 23 de niveau mineur et 1 cas où une notice ne signale aucune interaction significative. Chaque entrée ci-dessous cite la phrase sur laquelle elle repose. Cette page consacrée à un médicament est un point de départ, pas un verdict sur votre situation.

Interactions d'après la notice

Interactions majeures (6)

  • NéomycineaminosideMajeure

    The possibility of the occurrence of neuromuscular blockage and respiratory paralysis should be considered if neomycin is administered, especially to patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate anticoagulated blood. (notice Néomycine, Mise en garde encadrée)

  • PlazomicineaminosideMajeure

    During therapy with ZEMDRI, monitor for adverse reactions associated with neuromuscular blockade, particularly in high-risk patients, such as patients with underlying neuromuscular disorders (including myasthenia gravis) or in patients concomitantly receiving neuromuscular blocking agents [see Warning and Precautions (5.3) ] . (notice Plazomicine, Mise en garde encadrée)

  • QuinineantipaludiqueMajeure

    Avoid concomitant use with neuromuscular blocking agents. (notice Quinine, Mises en garde et précautions)

  • RémifentanilopioïdeMajeure

    In the case of life-threatening muscle rigidity, a rapid onset neuromuscular blocker or naloxone may be administered. (notice Rémifentanil, Mises en garde et précautions)

  • Rocuroniumbloquant neuromusculaireMajeure

    Rocuronium Bromide Injection is contraindicated in patients known to have hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents [see Warnings and Precautions ( 5.2 )] . (notice Rocuronium, Contre-indications)

  • SugammadexMajeure

    Reversal of Neuromuscular Blocking Agents Other Than Rocuronium or Vecuronium Do not use BRIDION to reverse blockade induced by nonsteroidal neuromuscular blocking agents such as succinylcholine or benzylisoquinolinium compounds. (notice Sugammadex, Mises en garde et précautions)

Interactions modérées (41)

  • Atracuriumbloquant neuromusculaireModérée

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (notice Vécuronium, Mises en garde)

  • BaclofènemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • Butalbital et paracétamolbarbituriqueModérée

    Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • CarisoprodolmyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • ChlorzoxazonemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • Cisatracuriumbloquant neuromusculaireModérée

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (notice Vécuronium, Mises en garde)

  • ClindamycineantibiotiqueModérée

    • Neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. (notice Clindamycine, Interactions médicamenteuses)

  • CyclobenzaprinemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • DantrolènemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • DéflazacortcorticoïdeModérée

    Myopathy Patients receiving corticosteroids, including EMFLAZA, and concomitant therapy with neuromuscular blocking agents (e.g., pancuronium) or patients with disorders of neuromuscular transmission (e.g., myasthenia gravis) may be at increased risk of developing acute myopathy. (notice Déflazacort, Mises en garde et précautions)

  • Desfluraneanesthésique généralModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • Étomidateanesthésique généralModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • FentanylopioïdeModérée

    • Risks of Skeletal Muscle Rigidity and Skeletal Muscle Movement : Manage with neuromuscular blocking agent. (notice Fentanyl, Mises en garde et précautions)

  • IncobotulinumtoxinAbloquant neuromusculaireModérée

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (notice Vécuronium, Mises en garde)

  • Isofluraneanesthésique généralModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • Kétaminedépresseur du SNCModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • LincomycineantibiotiqueModérée

    Drug Interactions Lincomycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; therefore, it should be used with caution in patients receiving such agents. (notice Lincomycine, Interactions médicamenteuses)

  • Lithiummédicament sérotoninergiqueModérée

    Neuromuscular Blocking Agents Clinical Impact: Lithium may prolong the effects of neuromuscular blocking agents. (notice Lithium, Interactions médicamenteuses)

  • MétaxalonemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • MéthocarbamolmyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • MéthohexitalbarbituriqueModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • OnabotulinumtoxinAbloquant neuromusculaireModérée

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (notice Vécuronium, Mises en garde)

  • OrphénadrinemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • PhénobarbitalbarbituriqueModérée

    Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • Pipéracilline et tazobactamantibiotique de la famille des pénicillinesModérée

    Vecuronium Piperacillin when used concomitantly with vecuronium has been implicated in the prolongation of the neuromuscular blockade of vecuronium. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

  • PrimidoneanticonvulsivantModérée

    Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (notice Vécuronium, Précautions)

  • ProcaïnamideantiarythmiqueModérée

    Patients taking PA who require neuromuscular blocking agents such as succinylcholine may require less than usual doses of the latter, due to PA effects on reducing acetylcholine release. (notice Procaïnamide, Interactions médicamenteuses)

  • Propofoldépresseur du SNCModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • Pyridostigmineinhibiteur de la cholinestéraseModérée

    Depolarizing neuromuscular blocking agents: Increased effect. (notice Pyridostigmine, Interactions médicamenteuses)

  • QuinidineantiarythmiqueModérée

    Quinidine potentiates the actions of depolarizing (succinylcholine, decamethonium) and non-depolarizing ( d -tubocurarine, pancuronium) neuromuscular blocking agents . (notice Quinidine, Interactions médicamenteuses)

  • Sévofluraneanesthésique généralModérée

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (notice Vécuronium, Précautions)

  • Suxaméthoniumbloquant neuromusculaireModérée

    Drug Interactions Prior administration of succinylcholine may enhance the neuromuscular blocking effect of vecuronium and its duration of action. (notice Vécuronium, Interactions médicamenteuses)

  • TizanidinemyorelaxantModérée

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (notice Vécuronium, Mises en garde)

  • Toxine botulinique de type Abloquant neuromusculaireModérée

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (notice Vécuronium, Mises en garde)

  • Vérapamilinhibiteur calciqueModérée

    Neuromuscular Blocking Agents Clinical data and animal studies suggest that verapamil may potentiate the activity of neuromuscular blocking agents (curare-like and depolarizing). (notice Vérapamil, Interactions médicamenteuses)

Mentions mineures (23)

  • AmikacineaminosideMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • BacitracineantibiotiqueMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • CarbamazépineanticonvulsivantMineure

    N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine. (notice Carbamazépine, Interactions médicamenteuses)

  • Colistiméthate sodiqueantibiotiqueMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • Déméclocyclineantibiotique de la famille des tétracyclinesMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • Dextrométhorphane et quinidinemédicament sérotoninergiqueMineure

    Other Experience concerning injection of quinidine during recovery from use of other muscle relaxants suggests that recurrent paralysis may occur. (notice Vécuronium, Précautions)

  • Digoxineglycoside digitaliqueMineure

    Norepinephrine Dopamine Neuromuscular Blocking Agents Succinylcholine May cause sudden extrusion of potassium from muscle cells causing arrhythmias in patients taking digoxin. (notice Digoxine, Interactions médicamenteuses)

  • Donépézilinhibiteur de la cholinestéraseMineure

    A synergistic effect may be expected with concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists ( 7.2 ) (notice Donépézil, Interactions médicamenteuses)

  • DoxapramMineure

    In patients who have received neuromuscular blocking agents, doxapram may temporarily mask the residual effects of these drugs. (notice Doxapram, Interactions médicamenteuses)

  • Doxycyclineantibiotique de la famille des tétracyclinesMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • FosphénytoïneanticonvulsivantMineure

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (notice Fosphénytoïne, Interactions médicamenteuses)

  • Galantamineinhibiteur de la cholinestéraseMineure

    Anesthesia Galantamine, as a cholinesterase inhibitor, is likely to exaggerate the neuromuscular blocking effects of succinylcholine-type and similar neuromuscular blocking agents during anesthesia. (notice Galantamine, Mises en garde et précautions)

  • GentamicineaminosideMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • MagnésiumVitamines et minérauxMineure

    Magnesium salts, administered for the management of toxemia of (notice Vécuronium, Précautions)

  • Mémantine et donépézilinhibiteur de la cholinestéraseMineure

    Concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists may lead to synergistic effect. (notice Mémantine et donépézil, Interactions médicamenteuses)

  • Minocyclineantibiotique de la famille des tétracyclinesMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • PhénytoïneanticonvulsivantMineure

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (notice Phénytoïne, Interactions médicamenteuses)

  • Polymyxine BantibiotiqueMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • Tétracyclineantibiotique de la famille des tétracyclinesMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • Tigécyclineantibiotique de la famille des tétracyclinesMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

  • TobramycineaminosideMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

Aucune interaction significative signalée (1)

  • Dexmédétomidineagoniste alpha-adrénergiqueAucune interaction

    Neuromuscular Blockers In one study of 10 healthy adult volunteers, administration of PRECEDEX for 45 minutes at a plasma concentration of one ng/mL resulted in no clinically meaningful increases in the magnitude of neuromuscular blockade associated with rocuronium administration. (notice Dexmédétomidine, Interactions médicamenteuses)

Vérifiez Vécuronium avec tout ce que vous prenez. Ajoutez votre liste complète ; toutes les paires sont vérifiées en une fois.

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Ceci n'est pas un avis médical. Le niveau de gravité reflète la formulation de la notice, pas votre situation. Une alerte « majeure » peut être courante sous surveillance et une alerte « mineure » peut compter à forte dose. Demandez conseil à un pharmacien.