Interações de Vecurônio

Vecurônio, bloqueador neuromuscular, tem 71 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 6; moderadas: 41; leves: 23; casos em que uma bula relata não haver interação significativa: 1). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (6)

  • NeomicinaaminoglicosídeoGrave

    The possibility of the occurrence of neuromuscular blockage and respiratory paralysis should be considered if neomycin is administered, especially to patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate anticoagulated blood. (bula de Neomicina, Advertência em caixa preta)

  • PlazomicinaaminoglicosídeoGrave

    During therapy with ZEMDRI, monitor for adverse reactions associated with neuromuscular blockade, particularly in high-risk patients, such as patients with underlying neuromuscular disorders (including myasthenia gravis) or in patients concomitantly receiving neuromuscular blocking agents [see Warning and Precautions (5.3) ] . (bula de Plazomicina, Advertência em caixa preta)

  • QuininaantimaláricoGrave

    Avoid concomitant use with neuromuscular blocking agents. (bula de Quinina, Advertências e precauções)

  • RemifentanilaopioideGrave

    In the case of life-threatening muscle rigidity, a rapid onset neuromuscular blocker or naloxone may be administered. (bula de Remifentanila, Advertências e precauções)

  • Rocurôniobloqueador neuromuscularGrave

    Rocuronium Bromide Injection is contraindicated in patients known to have hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents [see Warnings and Precautions ( 5.2 )] . (bula de Rocurônio, Contraindicações)

  • Reversal of Neuromuscular Blocking Agents Other Than Rocuronium or Vecuronium Do not use BRIDION to reverse blockade induced by nonsteroidal neuromuscular blocking agents such as succinylcholine or benzylisoquinolinium compounds. (bula de Sugamadex, Advertências e precauções)

Interações moderadas (41)

  • Atracúriobloqueador neuromuscularModerada

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Vecurônio, Advertências)

  • Baclofenorelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • Butalbital + paracetamolbarbitúricoModerada

    Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • Carisoprodolrelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Cetaminadepressor do SNCModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • Ciclobenzaprinarelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Cisatracúriobloqueador neuromuscularModerada

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Vecurônio, Advertências)

  • ClindamicinaantibióticoModerada

    • Neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. (bula de Clindamicina, Interações medicamentosas)

  • Clorzoxazonarelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Dantrolenorelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • DeflazacortecorticosteroideModerada

    Myopathy Patients receiving corticosteroids, including EMFLAZA, and concomitant therapy with neuromuscular blocking agents (e.g., pancuronium) or patients with disorders of neuromuscular transmission (e.g., myasthenia gravis) may be at increased risk of developing acute myopathy. (bula de Deflazacorte, Advertências e precauções)

  • Desfluranoanestésico geralModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • Etomidatoanestésico geralModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • FenobarbitalbarbitúricoModerada

    Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • FentanilaopioideModerada

    • Risks of Skeletal Muscle Rigidity and Skeletal Muscle Movement : Manage with neuromuscular blocking agent. (bula de Fentanila, Advertências e precauções)

  • Isofluranoanestésico geralModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • LincomicinaantibióticoModerada

    Drug Interactions Lincomycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; therefore, it should be used with caution in patients receiving such agents. (bula de Lincomicina, Interações medicamentosas)

  • Lítiomedicamento serotoninérgicoModerada

    Neuromuscular Blocking Agents Clinical Impact: Lithium may prolong the effects of neuromuscular blocking agents. (bula de Lítio, Interações medicamentosas)

  • Metaxalonarelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Metocarbamolrelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • MetoexitalbarbitúricoModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • Orfenadrinarelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasModerada

    Vecuronium Piperacillin when used concomitantly with vecuronium has been implicated in the prolongation of the neuromuscular blockade of vecuronium. (bula de Piperacilina + tazobactam, Interações medicamentosas)

  • Piridostigminainibidor da colinesteraseModerada

    Depolarizing neuromuscular blocking agents: Increased effect. (bula de Piridostigmina, Interações medicamentosas)

  • PrimidonaanticonvulsivanteModerada

    Thiopental Reconstituted vecuronium, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions such as thiopental) in the same syringe or administered simultaneously during intravenous infusion through the same needle or through the same intravenous line (see DOSAGE AND ADMINISTRATION -COMPATIBILITY ). (bula de Vecurônio, Precauções)

  • ProcainamidaantiarrítmicoModerada

    Patients taking PA who require neuromuscular blocking agents such as succinylcholine may require less than usual doses of the latter, due to PA effects on reducing acetylcholine release. (bula de Procainamida, Interações medicamentosas)

  • Propofoldepressor do SNCModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • QuinidinaantiarrítmicoModerada

    Quinidine potentiates the actions of depolarizing (succinylcholine, decamethonium) and non-depolarizing ( d -tubocurarine, pancuronium) neuromuscular blocking agents . (bula de Quinidina, Interações medicamentosas)

  • Sevofluranoanestésico geralModerada

    Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade. (bula de Vecurônio, Precauções)

  • Suxametônio (succinilcolina)bloqueador neuromuscularModerada

    Drug Interactions Prior administration of succinylcholine may enhance the neuromuscular blocking effect of vecuronium and its duration of action. (bula de Vecurônio, Interações medicamentosas)

  • Tizanidinarelaxante muscularModerada

    In such patients, a peripheral nerve stimulator and use of a small test dose may be of value in monitoring the response to administration of muscle relaxants. (bula de Vecurônio, Advertências)

  • Toxina botulínica tipo Abloqueador neuromuscularModerada

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Vecurônio, Advertências)

  • Toxina incobotulínica Abloqueador neuromuscularModerada

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Vecurônio, Advertências)

  • Toxina onabotulínica Abloqueador neuromuscularModerada

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Vecurônio, Advertências)

  • Verapamilbloqueador dos canais de cálcioModerada

    Neuromuscular Blocking Agents Clinical data and animal studies suggest that verapamil may potentiate the activity of neuromuscular blocking agents (curare-like and depolarizing). (bula de Verapamil, Interações medicamentosas)

Menções leves (23)

  • AmicacinaaminoglicosídeoLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • BacitracinaantibióticoLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • CarbamazepinaanticonvulsivanteLeve

    N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine. (bula de Carbamazepina, Interações medicamentosas)

  • ColistimetatoantibióticoLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • Demeclociclinaantibiótico da classe das tetraciclinasLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • Dextrometorfano + quinidinamedicamento serotoninérgicoLeve

    Other Experience concerning injection of quinidine during recovery from use of other muscle relaxants suggests that recurrent paralysis may occur. (bula de Vecurônio, Precauções)

  • Digoxinaglicosídeo digitálicoLeve

    Norepinephrine Dopamine Neuromuscular Blocking Agents Succinylcholine May cause sudden extrusion of potassium from muscle cells causing arrhythmias in patients taking digoxin. (bula de Digoxina, Interações medicamentosas)

  • Donepezilainibidor da colinesteraseLeve

    A synergistic effect may be expected with concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists ( 7.2 ) (bula de Donepezila, Interações medicamentosas)

  • In patients who have received neuromuscular blocking agents, doxapram may temporarily mask the residual effects of these drugs. (bula de Doxapram, Interações medicamentosas)

  • Doxiciclinaantibiótico da classe das tetraciclinasLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • FenitoínaanticonvulsivanteLeve

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (bula de Fenitoína, Interações medicamentosas)

  • FosfenitoínaanticonvulsivanteLeve

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (bula de Fosfenitoína, Interações medicamentosas)

  • Galantaminainibidor da colinesteraseLeve

    Anesthesia Galantamine, as a cholinesterase inhibitor, is likely to exaggerate the neuromuscular blocking effects of succinylcholine-type and similar neuromuscular blocking agents during anesthesia. (bula de Galantamina, Advertências e precauções)

  • GentamicinaaminoglicosídeoLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • MagnésioVitaminas e mineraisLeve

    Magnesium salts, administered for the management of toxemia of (bula de Vecurônio, Precauções)

  • Memantina + donepezilainibidor da colinesteraseLeve

    Concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists may lead to synergistic effect. (bula de Memantina + donepezila, Interações medicamentosas)

  • Minociclinaantibiótico da classe das tetraciclinasLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • Polimixina BantibióticoLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • Tetraciclinaantibiótico da classe das tetraciclinasLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • Tigeciclinaantibiótico da classe das tetraciclinasLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

  • TobramicinaaminoglicosídeoLeve

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)

Nenhuma interação significativa relatada (1)

  • Dexmedetomidinaagonista alfa-adrenérgicoSem interação

    Neuromuscular Blockers In one study of 10 healthy adult volunteers, administration of PRECEDEX for 45 minutes at a plasma concentration of one ng/mL resulted in no clinically meaningful increases in the magnitude of neuromuscular blockade associated with rocuronium administration. (bula de Dexmedetomidina, Interações medicamentosas)

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Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.