आइसोसॉर्बाइड मोनोनाइट्रेट के इंटरैक्शन

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Hypersensitivity to Nitroglycerin Lingual Spray or to other nitrates or nitrites or any excipient. (नाइट्रोग्लिसरीन लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking the soluble guanylate cyclase stimulator riociguat. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (अल्फुज़ोसिन लेबल, चेतावनियां और सावधानियां)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics… (आर्टिकेन और एड्रेनालिन लेबल, दवाओं के इंटरैक्शन)

Most cases reported product application with use under occlusion, genital application, or application to a large body surface area which may increase the systemic absorption of econazole nitrate. (इकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Co-administration of vaginal miconazole nitrate and Etonogestrel/Ethinyl Estradiol Vaginal Ring increases the serum concentrations of etonogestrel and ethinyl estradiol by up to 40% [see Clinical Pharmacology (12.3) ] . (एटोनोजेस्ट्रेल और एथिनिल एस्ट्राडियोल लेबल, दवाओं के इंटरैक्शन)

Hypotension Adenosine injection is a potent peripheral vasodilator and can induce significant hypotension. (एडेनोसिन लेबल, चेतावनियां और सावधानियां)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Valvular Stenosis There is concern, on theoretical grounds, that patients with aortic stenosis might be at particular risk of decreased coronary perfusion when treated with vasodilators because they do not develop as much afterload reduction as others. (कैप्टोप्रिल लेबल, सावधानियां)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (क्लोरोप्रोकेन लेबल, सावधानियां)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

…drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (डाइसाइक्लोमिन लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

• Co-administration with Other Vasodilators or Negative Chronotropic Agents : Use with caution due to additive pharmacodynamic effects. (डेक्समेडेटोमिडिन लेबल, चेतावनियां और सावधानियां)

…oral anticoagulants, calcium channel blockers, beta blockers, cardiac glycosides, inducers of CYP3A4, substrates and inhibitors of CYP3A4, substrates and inhibitors of P-glycoprotein, nitrates, sulphonylureas, loop diuretics, potassium sparing diuretics, thiazide diuretics, substrates and inhibitors of tubular organic cation transport, and QTc-prolonging drugs. (डोफेटिलाइड लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Caution should also be used when niacin extended-release tablets are used in patients with unstable angina or in the acute phase of an MI, particularly when such patients are also receiving vasoactive drugs such as nitrates, calcium channel blockers, or adrenergic blocking agents. (नियासिन लेबल, चेतावनियां और सावधानियां)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: EXAMPLES OF DRUGS ASSOCIATED WITH METHEMOGLOBINEMIA: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (प्रिलोकेन और एड्रेनालिन लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (ब्यूपिवाकेन लेबल, दवाओं के इंटरैक्शन)

• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (ब्यूपिवाकेन और एड्रेनालिन लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitroglycerin, nitroprusside, nitric oxide, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (मेपिवाकेन लेबल, दवाओं के इंटरैक्शन)

…exposed to the following drugs, which could include other local anesthetics [see Warnings and Precautions ( 5.4 )] : Examples of Drugs Associated with Methemoglobinemia Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (रोपिवाकेन लेबल, दवाओं के इंटरैक्शन)

Drugs Associated with Methemoglobinemia: Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (लिडोकेन और एड्रेनालिन लेबल, दवाओं के इंटरैक्शन)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (लिडोकेन और प्रिलोकेन लेबल, दवाओं के इंटरैक्शन)

Marked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Alcohol, in particular, has been found to exhibit additive effects of this variety. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

The vasodilating effects of isosorbide mononitrate may be additive with those of other vasodilators. (आइसोसॉर्बाइड मोनोनाइट्रेट लेबल, दवाओं के इंटरैक्शन)

Drugs antagonizing pressor effects of epinephrine α-blockers, such as phentolamine Vasodilators, such as nitrates Diuretics Antihypertensives Ergot alkaloids Drugs potentiating pressor effects of epinephrine • Sympathomimetics • β-blockers, such as propranolol • Tricyclic anti-depressants • Monoamine oxidase (MAO) inhibitors • Catechol-O-methyl transferase (COMT)… (एड्रेनालिन लेबल, दवाओं के इंटरैक्शन)

Other Cardiovascular Agents Enalapril has been used concomitantly with beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions. (एनालाप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Other Cardiovascular Agents Enalaprilat injection, USP has been used concomitantly with digitalis, beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions. (एनालाप्रिलैट लेबल, दवाओं के इंटरैक्शन)

Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (टैम्सुलोसिन लेबल, चेतावनियां और सावधानियां)

Alpha-adrenergic antagonists and PDE-5 inhibitors are both vasodilators that can lower blood pressure. (ड्यूटास्टेराइड और टैम्सुलोसिन लेबल, चेतावनियां और सावधानियां)

…acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives without evidence of clinically… (फिनास्टेराइड लेबल, दवाओं के इंटरैक्शन)

Post injury arterial injection of vasodilators and/or arterial infusion of parenteral fluids are generally regarded to be of no value in altering outcome. (मेथोहेक्सिटल लेबल, चेतावनियां)

Other Agents: Lisinopril has been used concomitantly with nitrates and/or digoxin without evidence of clinically significant adverse interactions. (लिसिनोप्रिल और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (सिलोडोसिन लेबल, चेतावनियां और सावधानियां)