एसाइक्लोविर और वैलासाइक्लोविर का इंटरैक्शन

CONTRAINDICATIONS Acyclovir tablets are contraindicated in patients who have demonstrated clinically significant hypersensitivity reaction [e.g., anaphylaxis, severe cutaneous adverse reactions (SCARs) to acyclovir, valacyclovir, or any component of the formulation (see WARNINGS and ADVERSE REACTIONS ).

Acyclovir tablets are contraindicated in patients who have developed SCARs with the use of acyclovir or valacyclovir, or any component of the formulation (see CONTRAINDICATIONS and ADVERSE REACTIONS ).

VALTREX is contraindicated in patients who have had a demonstrated clinically significant hypersensitivity reaction [e.g., anaphylaxis, severe cutaneous adverse reactions (SCARs)] to valacyclovir, acyclovir, or any component of the formulation [see Warnings and Precautions ( 5.4 ), Adverse Reactions ( 6.3 )] .

Hypersensitivity to valacyclovir (e.g., anaphylaxis), acyclovir, or any component of the formulation.

VALTREX is contraindicated in patients who have developed SCARs with the use of valacyclovir or acyclovir, or any component of the formulation [see Contraindications ( 4 ), Adverse Reactions ( 6.3 )] .

Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid.