शराब (अल्कोहल) और सैक्साग्लिप्टिन और मेटफॉर्मिन का इंटरैक्शन

…concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure ), excessive alcohol intake, hepatic impairment, and mitochondrial diseases [ see Warnings and Precautions (5.1) ].

• Risk factors include renal impairment, concomitant use of certain drugs, age > 65 years old, radiological studies with contrast, surgery and other procedures, hypoxic states, excessive alcohol intake, hepatic impairment, and mitochondrial diseases.

Excessive Alcohol Intake Alcohol potentiates the effect of metformin on lactate metabolism and this may increase the risk of metformin-associated lactic acidosis.

Metformin HCl Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, but could occur when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or during concomitant use with other glucose-lowering agents (such as sulfonylureas and insulin) or ethanol.

Alcohol Alcohol is known to potentiate the effect of metformin on lactate metabolism.

इंसुलिन या सल्फोनिलयूरिया के साथ शराब से ब्लड शुगर कम हो सकती है, और मेटफॉर्मिन के साथ भारी मात्रा में शराब पीने से लैक्टिक एसिडोसिस का जोखिम बढ़ता है।

लेबल का मूल पाठ (अंग्रेज़ी) Alcohol can cause low blood sugar with insulin or sulfonylureas, and heavy drinking with metformin raises the risk of lactic acidosis.