एल्टेप्लेज़ और वारफेरिन का इंटरैक्शन

…hemorrhagic ophthalmic conditions Septic thrombophlebitis or occluded AV cannula at seriously infected site Advanced age [see Use in Specific Populations (8.5) ] Patients currently receiving anticoagulants (e.g., warfarin sodium) Any other condition in which bleeding constitutes a significant hazard or would be particularly difficult to manage because of its location.

Anticoagulants and antiplatelet drugs increase the risk of bleeding if administered prior to, during, or after Activase therapy.

Anticoagulants and drugs that inhibit platelet function increase the risk of bleeding when administered with Activase therapy.

Hemorrhage can occur 1 or more days after administration of Activase, while patients are still receiving anticoagulant therapy.

It is associated with invasive vascular procedures (e.g., cardiac catheterization, angiography, vascular surgery) and/or anticoagulant therapy.