एप्रेपिटेंट और बोसुटिनिब का इंटरैक्शन

• Strong and Moderate CYP3A Inhibitors: Avoid concomitant use with BOSULIF.

• Strong CYP3A Inducers: Avoid concomitant use with BOSULIF.

Effect of Other Drugs on BOSULIF Strong or Moderate CYP3A Inhibitors Avoid the concomitant use of strong or moderate CYP3A inhibitors with BOSULIF.

Strong CYP3A Inducers Avoid the concomitant use of strong CYP3A inducers with BOSULIF.

Concomitant use with a strong or moderate CYP3A inhibitor increases bosutinib C max and AUC [see Clinical Pharmacology (12.3) ] which may increase the risk of toxicities.