ब्यूटाल्बिटल, एस्पिरिन, कैफीन और कोडीन और आइबुप्रोफेन और फैमोटिडीन का इंटरैक्शन

History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.

History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Exacerbation of Asthma Related to Aspirin Sensitivity : Ibuprofen and famotidine tablet are contraindicated in patients with aspirin-sensitive asthma.

Exacerbation of Asthma Related to Aspirin Sensitivity A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polyps; severe, potentially fatal bronchospasm; and/or intolerance to aspirin and other NSAIDs.

Because cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, ibuprofen and famotidine tablet is contraindicated in patients with this form of aspirin sensitivity [see Contraindications (4)].

Examples: Ketorolac, ibuprofen, naproxen, diclofenac Corticosteroids Clinical Impact: In patients receiving concomitant corticosteroids and chronic use of aspirin, withdrawal of corticosteroids may result in salicylism because corticosteroids enhance renal clearance of salicylates and their withdrawal is followed by return to normal rates of renal clearance.