डोनेपेज़िल और पाइरिडोस्टिग्मिन का इंटरैक्शन

Pyridostigmine bromide extended-release tablets are contraindicated in patients with: Mechanical intestinal or urinary obstruction Known hypersensitivity to pyridostigmine or other anticholinesterase agents Mechanical intestinal or urinary obstruction.

Known hypersensitivity to pyridostigmine or other anticholinesterase agents.

Other Anticholinesterase Drugs Concomitant use of anticholinesterase drugs used in the treatment of glaucoma and pyridostigmine bromide may have an additive effect that may cause or exacerbate problems with night vision.

Peptic Ulcer Disease and GI Bleeding Through their primary action, cholinesterase inhibitors may be expected to increase gastric acid secretion due to increased cholinergic activity.

Cholinomimetics may cause bladder outflow obstructions ( 5.6 )

Cholinomimetics are believed to have some potential to cause generalized convulsions ( 5.7 )

Genitourinary Conditions Although not observed in clinical trials of ARICEPT, cholinomimetics may cause bladder outflow obstruction.

Neurological Conditions: Seizures Cholinomimetics are believed to have some potential to cause generalized convulsions.