डोरज़ोलामाइड और टिमोलोल और पियोग्लिटाज़ोन और ग्लिमेपिराइड का इंटरैक्शन

Use in patients with known history of an allergic reaction to sulfonamide derivatives.

Hypersensitivity to sulfonamide derivatives.

…steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors.

The signs of hypoglycemia may be reduced or absent in patients taking sympatholytic drugs such as beta-blockers, clonidine, guanethidine, and reserpine.

Beta-blockers, clonidine, and reserpine may lead to either potentiation or weakening of pioglitazone and glimepiride tablets glucose-lowering effect.

Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Beta-adrenergic blocking agents should be administered with caution in patients subject to spontaneous hypoglycemia or to diabetic patients (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic agents.