डॉक्साज़ोसिन और इट्राकोनाज़ोल का इंटरैक्शन

…that Affect Concomitant Drug Concentrations Concomitant Drug Within Class Prevention or Management Drug Interactions with TOLSURA that Increase Concomitant Drug Concentrations and May Increase Risk of Adverse Reactions Associated with the Concomitant Drug Alpha Blockers Alfuzosin Silodosin Tamsulosin Not recommended during and 2 weeks after TOLSURA treatment.

Strong cytochrome P450 (CYP) 3A inhibitors may increase exposure to doxazosin and increased risk of hypotension.

Strong CYP3A inhibitors may increase exposure to doxazosin.

Monitor blood pressure and for symptoms of hypotension when Doxazosin is used concomitantly with strong CYP3A inhibitors [see Clinical Pharmacology (12.3) ].

CYP 3A Inhibitors In vitro studies suggest that doxazosin is a substrate of CYP 3A4.