एस्सिटालोप्राम और लिथियम का इंटरैक्शन

Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone.

If concomitant use of Escitalopram Capsules with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms.

Other Serotonergic Drugs Prevention or Management Monitor patients for signs and symptoms of serotonin syndrome, particularly during escitalopram initiation and dosage increases.

Lithium Prevention or Management Monitor plasma lithium levels with appropriate adjustment to the lithium dose in accordance with standard clinical practice.

Mechanism and Clinical Effect(s) Because lithium may enhance the serotonergic effects of escitalopram, caution should be exercised when Escitalopram Capsules is used concomitantly with lithium.

If concomitant use of lithium with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms.

• Serotonergic Agents: Increased risk of serotonin syndrome when co-administered with lithium.

Serotonergic Drugs Clinical Impact: Concomitant use can precipitate serotonin syndrome.

If serotonin syndrome occurs, consider discontinuation of lithium and/or concomitant serotonergic drugs [see Warnings and Precautions ( 5.6 )] .

The risk is increased with concomitant use of other serotonergic drugs (including selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, triptans, tricyclic antidepressants, fentanyl, tramadol, tryptophan, buspirone, and St.