एस्ज़ोपिक्लोन और फ्लुफेनाज़िन का इंटरैक्शन

The use of LUNESTA with other sedative-hypnotics at bedtime or the middle of the night is not recommended.

CNS Depressant Effects: Impaired alertness and motor coordination, including risk of morning impairment.

Risk increases with dose and use with other CNS depressants and alcohol.

Post-marketing reports have shown that complex sleep behaviors may occur with LUNESTA alone at recommended dosages, with or without the concomitant use of alcohol or other CNS depressants [see Drug Interactions ( 7.1 )] .

CNS Depressant Effects and Next-Day Impairment LUNESTA is a CNS depressant and can impair daytime function in some patients at the higher doses (2 mg or 3 mg), even when used as prescribed.

CONTRAINDICATIONS Phenothiazines are contraindicated in patients with suspected or established subcortical brain damage, in patients receiving large doses of hypnotics, and in comatose or severely depressed states.

Moreover, it should be remembered that reduced amounts of anesthetics or central nervous system depressants may be necessary.