फ्लुकोनाज़ोल और लोरलाटिनिब का इंटरैक्शन

• Fluconazole : Avoid concomitant use; reduce LORBRENA dose if concomitant use cannot be avoided.

Fluconazole Avoid concomitant use of LORBRENA with fluconazole.

• Strong CYP3A Inhibitors : Avoid concomitant use; reduce LORBRENA dose if concomitant use cannot be avoided.

Strong CYP3A Inhibitors Avoid concomitant use of LORBRENA with a strong CYP3A inhibitor.

Concomitant use of LORBRENA with fluconazole may increase lorlatinib plasma concentrations [see Clinical Pharmacology (12.3) ] , which may increase the incidence and severity of adverse reactions of LORBRENA.