फ्लुकोनाज़ोल और प्रोपाफेनोन का इंटरैक्शन

• Avoid use with other antiarrhythmic agents or drugs that prolong the QT interval.

• Avoid simultaneous use of propafenone with both a cytochrome P450 2D6 (CYP2D6) inhibitor and a 3A4 inhibitor (CYP3A4).

Therefore, avoid simultaneous use of propafenone hydrochloride extended-release capsules with both a CYP2D6 inhibitor and a CYP3A4 inhibitor.

Therefore, simultaneous use of propafenone hydrochloride extended-release capsules with both a CYP2D6 inhibitor and a CYP3A4 inhibitor should be avoided [see Warnings and Precautions ( 5.4 ) and Dosage and Administration ( 2 )].

It may also worsen premature ventricular contractions or supraventricular arrhythmias, and it may prolong the QT interval.