फ्लुकोनाज़ोल और रक्सोलिटिनिब का इंटरैक्शन

Fluconazole: Avoid concomitant use with fluconazole doses greater than 200 mg.

Avoid concomitant use of JAKAFI/JAKAFI XR with fluconazole doses of greater than 200 mg daily.

Reduce JAKAFI/JAKAFI XR dosage with fluconazole doses less than or equal to 200 mg.

Effect of Other Drugs on JAKAFI/JAKAFI XR Fluconazole Concomitant use of JAKAFI/JAKAFI XR with fluconazole increases ruxolitinib exposure [ see Clinical Pharmacology ( 12.3 )] , which may increase the risk of exposure-related adverse reactions.

Reduce the JAKAFI/JAKAFI XR dosage when used concomitantly with fluconazole doses of less than or equal to 200 mg [ see Dosage and Administration ( 2.6 )] .