फ्लर्बिप्रोफेन और हाइड्रोकॉर्टिसोन का इंटरैक्शन

Concurrent administration of corticosteroids with non-steroidal anti-inflammatory drugs (NSAIDS) may increase the risk of gastrointestinal adverse reactions.

Monitor patients receiving corticosteroids and concomitant NSAIDS for gastrointestinal adverse reactions [see Drug Interactions ( 7 )] .

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Clinical Impact: Concomitant use of NSAIDs and corticosteroids increases the risk of gastrointestinal adverse reactions.

Intervention: Monitor patients receiving ALKINDI SPRINKLE and concomitant NSAIDs.

NSAIDs: concomitant administration increases risk of gastrointestinal adverse reactions.

Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking, use of alcohol, older age, and poor general health status.

Corticosteroids Clinical Impact: Concomitant use of corticosteroids with flurbiprofen may increase the risk of GI ulceration or bleeding.

Intervention: Monitor patients with concomitant use of flurbiprofen with corticosteroids for signs of bleeding [ see Warnings and Precautions (5.2) ].