इरिनोटेकन और लोपेरामाइड का इंटरैक्शन

Late diarrhea can be life threatening and should be treated promptly with loperamide.

Loperamide is not recommended to be used for more than 48 consecutive hours at these doses, because of the risk of paralytic ileus.

One dosage regimen for loperamide is 4 mg at the first onset of late diarrhea and then 2 mg every 2 hours until the patient is diarrhea-free for at least 12 hours.

Treat with loperamide.

Patients should have loperamide readily available to begin treatment for late diarrhea.