लोसार्टन और रिफैम्पिसिन का इंटरैक्शन

However, rifampin has been shown to decrease the AUC of losartan and its active metabolite by 30% and 40%, respectively.

Substitute non-enzyme inducing therapies at least 2 weeks prior to initiation of irinotecan therapy Decrease irinotecan and active metabolite exposure Levothyroxine Decrease exposure Losartan Parent Decrease AUC by 30% Active metabolite (E3174) Decrease AUC by 40% Methadone In patients well-stabilized on methadone, concomitant administration of rifampin resulted…