मेथएम्फेटामाइन और रासाजिलिन का इंटरैक्शन

Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6 )]. taking monoamine oxidase inhibitors (MAOIs), or within 14 days following discontinuation of treatment with an MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because…

Concomitant use of monoamine oxidase inhibitors (MAOIs), or use of an MAOI within the preceding 14 days.

Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations.

Concomitant use of methamphetamine with MAOI drugs is contraindicated [see Contraindications (4)].

Intervention: Concomitant use of methamphetamine hydrochloride tablets, USP with monoamine oxidase inhibitors (MAOIs) or within 14 days after discontinuing MAOI treatment is contraindicated [see Contraindications (4)].

Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications.

Severe hypertension has been reported in patients taking the recommended dose of rasagiline and ophthalmic drops containing sympathomimetic medications.

Nevertheless, caution should be exercised when concomitantly using recommended doses of rasagiline with any sympathomimetic medications including nasal, oral, and ophthalmic decongestants and cold remedies.

Sympathomimetic Medications The concomitant use of rasagiline and sympathomimetic medications was not allowed in clinical studies.

Severe hypertensive reactions have followed the administration of sympathomimetics and nonselective MAO inhibitors.