मिथाइलटेस्टोस्टेरोन और टेस्टोस्टेरोन का इंटरैक्शन

To date, epidemiologic studies and randomized controlled trials have been inconclusive for determining the risk of major adverse cardiovascular events (MACE), such as non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death, with the use of testosterone compared to non-use.

Testosterone products are not recommended for use in patients with uncontrolled hypertension.

Some studies, but not all, have reported an increased risk of MACE in association with use of testosterone replacement therapy in men.

Testosterone can increase blood pressure which can increase cardiovascular (CV) risk over time.

Monitor blood pressure periodically in men using testosterone products, especially in men with hypertension.

Hepatic Adverse Effects Prolonged use of high doses of orally active 17-alpha-alkyl androgens (e.g., methyltestosterone) has been associated with serious hepatic adverse effects (peliosis hepatis, hepatic neoplasms, cholestatic hepatitis, and jaundice).