पाज़ोपैनिब और सोडियम बाइकार्बोनेट का इंटरैक्शन

Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents.

Avoid concomitant use of VOTRIENT with gastric acid-reducing agents.

If concomitant administration with a gastric acid-reducing agent cannot be avoided, consider short-acting antacids in place of PPIs and H2-receptor antagonists.

Separate short-acting antacid and pazopanib dosing by several hours to avoid a reduction in pazopanib exposure [see Dosage and Administration (2.4), Clinical Pharmacology (12.3)] .

Consider short-acting antacids in place of proton pump inhibitors (PPIs) and H2-receptor antagonists.