पाज़ोपैनिब और वेरापामिल का इंटरैक्शन

Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors.

Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors and consider an alternate concomitant medication with no or minimal enzyme inhibition potential.

If coadministration of a strong CYP3A4 inhibitor cannot be avoided, reduce the dose of VOTRIENT [see Dosage and Administration (2.4)] .

Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP.

Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate.