Interaksi Benazepril dan hidroklorotiazid

Benazepril dan hidroklorotiazid (Lotensin HCT), golongan penghambat ACE, memiliki 464 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 75 mayor, 343 moderat, 44 minor, dan 2 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (75)

  • AliskirenantihipertensiMayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Amiloriddiuretik hemat kaliumMayor

    Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (label Amilorid, Peringatan kotak hitam)

  • Amlodipin dan benazeprilpenghambat kanal kalsium dihidropiridinMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Amlodipin dan olmesartanpenghambat kanal kalsium dihidropiridinMayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Amlodipin dan valsartanpenghambat kanal kalsium dihidropiridinMayor

    Do not administer Lotensin HCT within 36 hours of switching to or from sacubitril/valsartan, a neprilysin inhibitor (see WARNINGS and PRECAUTIONS ). (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Arsen trioksidaobat yang memperpanjang interval QTMayor

    The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (label Arsen trioksida, Peringatan dan perhatian)

  • Asam etakrinatdiuretik loopMayor

    CONTRAINDICATIONS All diuretics, including ethacrynic acid, are contraindicated in anuria. (label Asam etakrinat, Kontraindikasi)

  • Asetazolamidpenghambat karbonat anhidraseMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Azilsartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Benazeprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Brinzolamidpenghambat karbonat anhidraseMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Bumetaniddiuretik loopMayor

    WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (label Bumetanid, Peringatan kotak hitam)

  • CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (label Diazoksid, Kontraindikasi)

  • Diklorfenamidpenghambat karbonat anhidraseMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • DofetilidantiaritmiaMayor

    The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (label Dofetilid, Kontraindikasi)

  • Dorzolamidpenghambat karbonat anhidraseMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Dorzolamid dan timololpenghambat karbonat anhidraseMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Droperidolantagonis dopaminMayor

    Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (label Droperidol, Peringatan kotak hitam)

  • Enalaprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Enalaprilatpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Eplerenonantagonis aldosteronMayor

    …• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (label Eplerenon, Kontraindikasi)

  • EptifibatidantiplateletMayor

    …of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (label Eptifibatid, Kontraindikasi)

  • EverolimusimunosupresanMayor

    Avoid the concomitant use of ACE inhibitors with AFINITOR/AFINITOR DISPERZ [see Warnings and Precautions (5.4)] . (label Everolimus, Interaksi obat)

  • Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (label Folitropin, Peringatan dan perhatian)

  • Fosinoprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • GentamisinaminoglikosidaMayor

    The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (label Gentamisin, Peringatan kotak hitam)

  • Hidroklorotiaziddiuretik tiazidMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Irbesartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Irbesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Avoid diuretics or laxatives in patients with diarrhea. (label Irinotekan, Peringatan dan perhatian)

  • Itrakonazolantijamur azolMayor

    Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (label Itrakonazol, Interaksi obat)

  • KaliumVitamin dan mineralMayor

    Obat-obat ini mengurangi ekskresi kalium; menambahkan suplemen kalium atau garam pengganti dapat menyebabkan hiperkalemia, yang memengaruhi irama jantung. (NIH Office of Dietary Supplements, Potassium)

  • Kalium sitratsuplemen kaliumMayor

    The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (label Kalium sitrat, Interaksi obat)

  • Kandesartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Kandesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Kaptoprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • KlozapinantipsikotikMayor

    Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (label Klozapin, Peringatan kotak hitam)

  • Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (label Koriogonadotropin alfa, Peringatan)

  • Kuinaprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lisinoprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Losartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Losartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Metazolamidpenghambat karbonat anhidraseMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Metolazondiuretik tiazidMayor

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (label Metolazon, Peringatan)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • MinoksidilvasodilatorMayor

    Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (label Minoksidil, Peringatan kotak hitam)

  • Moeksiprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Natrium bikarbonatantasidaMayor

    Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (label Natrium bikarbonat, Kontraindikasi)

  • NeomisinaminoglikosidaMayor

    The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (label Neomisin, Peringatan kotak hitam)

  • Olmesartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Olmesartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Olmesartan, amlodipin, dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Perak sulfadiazinsulfonamidaMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Perindoprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Ramiprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Sakubitril dan valsartanpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is contraindicated in combination with a neprilysin inhibitor (e.g., sacubitril). (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • SiklosporinimunosupresanMayor

    Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (label Siklosporin, Interaksi obat)

  • Spironolakton dan hidroklorotiazidantagonis aldosteronMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • SulfadiazinsulfonamidaMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • SulfasalazinsulfonamidaMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Tadalafilpenghambat PDE5Mayor

    …coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (label Tadalafil, Peringatan dan perhatian)

  • Telmisartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Telmisartan dan amlodipinpenghambat reseptor angiotensin II (ARB)Mayor

    Do not coadminister aliskiren with angiotensin receptor blockers, ACE inhibitors, including Lotensin HCT in patients with diabetes. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Telmisartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Trandolaprilpenghambat ACEMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Triamteren dan hidroklorotiaziddiuretik hemat kaliumMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Valsartanpenghambat reseptor angiotensin II (ARB)Mayor

    Do not administer Lotensin HCT within 36 hours of switching to or from sacubitril/valsartan, a neprilysin inhibitor (see WARNINGS and PRECAUTIONS ). (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • Valsartan dan hidroklorotiazidpenghambat reseptor angiotensin II (ARB)Mayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

  • ZonisamidantikonvulsanMayor

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (label Benazepril dan hidroklorotiazid, Kontraindikasi)

Interaksi moderat (343)

  • AkarbosaantidiabetesModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • AklidiniumantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alfuzosinpenyekat alfaModerat

    Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (label Alfuzosin, Peringatan dan perhatian)

  • AlkoholAlkoholModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alogliptinpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alogliptin dan metforminpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alopurinolpenghambat xantin oksidaseModerat

    Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (label Alopurinol, Peringatan dan perhatian)

  • AlteplaseModerat

    In the post-marketing setting, there have been reports of angioedema in patients (primarily patients with AIS) receiving concomitant angiotensin-converting enzyme inhibitors. [see Warnings and Precautions (5.2) ]. (label Alteplase, Interaksi obat)

  • AmantadinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • AmikasinaminoglikosidaModerat

    Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (label Amikasin, Interaksi obat)

  • AmiodaronantiaritmiaModerat

    Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (label Amiodaron, Peringatan dan perhatian)

  • Amitriptilinantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Amlodipinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Amlodipin dan atorvastatinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Amoksapinantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Amoksisilinantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Amoksisilin dan klavulanatantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Ampisilinantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Ampisilin dan sulbaktamantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Arformoterolagonis beta-adrenergikModerat

    Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (label Arformoterol, Interaksi obat)

  • AripiprazolantipsikotikModerat

    Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (label Aripiprazol, Interaksi obat)

  • Armodafinilstimulan SSPModerat

    There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (label Armodafinil, Peringatan dan perhatian)

  • Artikain dan epinefrinanestetik lokalModerat

    When involvement of the tongue, glottis, or larynx appears likely to cause airway obstruction, appropriate therapy, e.g., subcutaneous epinephrine injection 1:1000 (0.3 - 0.5 mL) should be promptly administered ( see PRECAUTIONS and ADVERSE REACTIONS ). (label Benazepril dan hidroklorotiazid, Peringatan)

  • Asam mefenamatOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Asam zoledronatbisfosfonatModerat

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (label Asam zoledronat, Peringatan dan perhatian)

  • Asebutololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • AsenapinantipsikotikModerat

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (label Asenapin, Peringatan dan perhatian)

  • AspirinOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Aspirin dan dipiridamolantiplateletModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Atenololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Atenolol dan klortalidonpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Atomoksetinpenghambat ambilan kembali norepinefrinModerat

    Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (label Atomoksetin, Interaksi obat)

  • AtropinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Atropin dan pralidoksimantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Avanafilpenghambat PDE5Moderat

    • Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (label Avanafil, Peringatan dan perhatian)

  • Baklofenpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Beksagliflozinpenghambat SGLT2Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Beladona dan opiumopioidModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Benzfetaminstimulan SSPModerat

    Amphetamines may decrease the hypotensive effect of antihypertensives. (label Benzfetamin, Interaksi obat)

  • Benzilpenisilin (penisilin G)antibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • BenztropinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Betaksololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Bisoprololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • BortezomibModerat

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (label Bortezomib, Peringatan dan perhatian)

  • BrekspiprazolantipsikotikModerat

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (label Brekspiprazol, Peringatan dan perhatian)

  • Brimonidinagonis alfa-adrenergikModerat

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (label Brimonidin, Interaksi obat)

  • Brimonidin dan timololagonis alfa-adrenergikModerat

    Other ACE inhibitors have had less than additive effects with beta-adrenergic blockers, presumably because drugs of both classes lower blood pressure by inhibiting parts of the renin-angiotensin system. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Bromokriptinagonis dopaminModerat

    Use caution in patients taking antihypertensive medications. (label Bromokriptin, Peringatan dan perhatian)

  • Budesonid dan formoterolkortikosteroidModerat

    Diuretics: Use with caution. (label Budesonid dan formoterol, Interaksi obat)

  • Bupivakain dan epinefrinanestetik lokalModerat

    When involvement of the tongue, glottis, or larynx appears likely to cause airway obstruction, appropriate therapy, e.g., subcutaneous epinephrine injection 1:1000 (0.3 - 0.5 mL) should be promptly administered ( see PRECAUTIONS and ADVERSE REACTIONS ). (label Benazepril dan hidroklorotiazid, Peringatan)

  • BuprenorfinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • ButorfanolopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dantrolenpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dapagliflozinpenghambat SGLT2Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dapagliflozin dan metforminpenghambat SGLT2Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DarifenasinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DeksklorfeniraminantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dekslansoprazolpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (label Dekslansoprazol, Peringatan dan perhatian)

  • Deksmetilfenidatstimulan SSPModerat

    • Antihypertensive Drugs: Monitor blood pressure. (label Deksmetilfenidat, Interaksi obat)

  • Desipraminantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (label Desmopresin, Interaksi obat)

  • DesvenlafaksinSNRIModerat

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (label Desvenlafaksin, Peringatan dan perhatian)

  • Dietilpropionstimulan SSPModerat

    The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (label Dietilpropion, Interaksi obat)

  • DifenhidraminantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DiflunisalOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Digoksinglikosida digitalisModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DiklofenakOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dikloksasilinantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Diltiazempenghambat kanal kalsiumModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • DimenhidrinatantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DisikloverinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DisopiramidantiaritmiaModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Doksazosinpenyekat alfaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Doksepinantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dokserkalsiferolanalog vitamin DModerat

    Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (label Dokserkalsiferol, Peringatan dan perhatian)

  • DoksilaminantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Doksilamin dan piridoksinantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drospirenon dan etinilestradiolkontrasepsi oralModerat

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (label Drospirenon dan etinilestradiol, Peringatan dan perhatian)

  • Dulaglutidagonis reseptor GLP-1Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • DuloksetinSNRIModerat

    The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (label Duloksetin, Peringatan dan perhatian)

  • Eksenatidagonis reseptor GLP-1Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • EluksadolinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Empagliflozinpenghambat SGLT2Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Empagliflozin dan metforminpenghambat SGLT2Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • EpinefrinsimpatomimetikModerat

    When involvement of the tongue, glottis, or larynx appears likely to cause airway obstruction, appropriate therapy, e.g., subcutaneous epinephrine injection 1:1000 (0.3 - 0.5 mL) should be promptly administered ( see PRECAUTIONS and ADVERSE REACTIONS ). (label Benazepril dan hidroklorotiazid, Peringatan)

  • Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (label Epoetin alfa, Peringatan dan perhatian)

  • Epoprostenolanalog prostaglandinModerat

    Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (label Epoprostenol, Interaksi obat)

  • EsitalopramSSRIModerat

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (label Esitalopram, Peringatan dan perhatian)

  • Esmololpenyekat betaModerat

    Other ACE inhibitors have had less than additive effects with beta-adrenergic blockers, presumably because drugs of both classes lower blood pressure by inhibiting parts of the renin-angiotensin system. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Esomeprazolpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (label Esomeprazol, Peringatan dan perhatian)

  • EtodolakOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Felodipinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Fenelzinpenghambat MAOModerat

    …hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (label Fenelzin, Peringatan)

  • FenilefrindekongestanModerat

    Antagonistic Effects (decrease in BIORPHEN blood pressure effect) can occur with α-adrenergic antagonists, phosphodiesterase Type 5 inhibitors, mixed α- and β-receptor antagonists, calcium channel blockers, benzodiazepines and ACE inhibitors, centrally acting sympatholytic agents. (label Fenilefrin, Interaksi obat)

  • FenobarbitalbarbituratModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Fenoksibenzaminpenyekat alfaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Fenoksimetilpenisilin (penisilin V)antibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • FenoprofenOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • FentanilopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Fentermin dan topiramatstimulan SSPModerat

    Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively. (label Fentermin dan topiramat, Interaksi obat)

  • FesoterodinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • FlavoksatantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • FludrokortisonkortikosteroidModerat

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (label Fludrokortison, Interaksi obat)

  • Flukonazolantijamur azolModerat

    Hydrochlorothiazide In a pharmacokinetic interaction study, coadministration of multiple-dose hydrochlorothiazide to healthy volunteers receiving fluconazole increased plasma concentrations of fluconazole by 40%. (label Flukonazol, Interaksi obat)

  • FluoksetinSSRIModerat

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (label Fluoksetin, Peringatan dan perhatian)

  • FlurbiprofenOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Flutikason dan salmeterolkortikosteroidModerat

    Diuretics: Use with caution. (label Flutikason dan salmeterol, Interaksi obat)

  • FluvoksaminSSRIModerat

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (label Fluvoksamin, Peringatan dan perhatian)

  • Formoterolagonis beta-adrenergikModerat

    • Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (label Formoterol, Interaksi obat)

  • FoskarnetantivirusModerat

    When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (label Foskarnet, Interaksi obat)

  • Furosemiddiuretik loopModerat

    Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (label Benazepril dan hidroklorotiazid, Peringatan)

  • GlibenklamidsulfonilureaModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Glibenklamid dan metforminsulfonilureaModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • GlikopironiumantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • GlimepiridsulfonilureaModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • GlipizidsulfonilureaModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Glipizid dan metforminsulfonilureaModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Guanfasinagonis alfa-adrenergikModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • HaloperidolantipsikotikModerat

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (label Haloperidol, Interaksi obat)

  • HidralazinvasodilatorModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • HidrokodonopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • HidroksizinantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • HidromorfonopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • HiosiaminantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • IbuprofenOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • IloperidonantipsikotikModerat

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (label Iloperidon, Peringatan dan perhatian)

  • Imipraminantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Indapamiddiuretik tiazidModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • IndometasinOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Insulin aspartinsulinModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Insulin degludekinsulinModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Insulin detemirinsulinModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Insulin glargininsulinModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Insulin lisproinsulinModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • IpratropiumantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Ipratropium dan salbutamolantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Isradipinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (label Kalium iodida, Interaksi obat)

  • Kalsitriolanalog vitamin DModerat

    Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (label Kalsitriol, Interaksi obat)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (label Kalsium klorida, Interaksi obat)

  • Kanagliflozinpenghambat SGLT2Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KarbamazepinantikonvulsanModerat

    Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (label Karbamazepin, Peringatan dan perhatian)

  • KarbidopaModerat

    Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (label Karbidopa, Interaksi obat)

  • Karbidopa dan levodopaobat dopaminergikModerat

    Antihypertensive drugs: May cause symptomatic postural hypotension. (label Karbidopa dan levodopa, Interaksi obat)

  • Karbidopa, levodopa, dan entakaponobat dopaminergikModerat

    Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (label Karbidopa, levodopa, dan entakapon, Interaksi obat)

  • KarbinoksaminantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KariprazinantipsikotikModerat

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (label Kariprazin, Peringatan dan perhatian)

  • Karisoprodolpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Karvedilolpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Ketokonazolantijamur azolModerat

    Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (label Ketokonazol, Interaksi obat)

  • KetoprofenOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KetorolakOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KlemastinantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KlofarabinantimetabolitModerat

    Consider use of diuretics and/or albumin. (label Klofarabin, Peringatan dan perhatian)

  • Klomipraminantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Klonidinagonis alfa-adrenergikModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Klordiazepoksid dan klidiniumbenzodiazepinModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KlorfeniraminantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Klorotiaziddiuretik tiazidModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • KlorpromazinantipsikotikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Klortalidondiuretik tiazidModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Klorzoksazonpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KodeinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Kolestipolsekuestran asam empeduModerat

    Single doses of either cholestyramine or colestipol resins bind the hydrochlorothiazide and reduce its absorption from the gastrointestinal tract by up to 85% and 43%, respectively. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Kolestiraminsekuestran asam empeduModerat

    Single doses of either cholestyramine or colestipol resins bind the hydrochlorothiazide and reduce its absorption from the gastrointestinal tract by up to 85% and 43%, respectively. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KuetiapinantipsikotikModerat

    Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (label Kuetiapin, Peringatan dan perhatian)

  • KuinidinantiaritmiaModerat

    Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (label Kuinidin, Interaksi obat)

  • Labetalolpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Lansoprazolpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (label Lansoprazol, Peringatan dan perhatian)

  • Lantanumpengikat fosfatModerat

    Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (label Lantanum, Interaksi obat)

  • LevomilnasipranSNRIModerat

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (label Levomilnasipran, Peringatan dan perhatian)

  • LevorfanolopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Levosalbutamolagonis beta-adrenergikModerat

    Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (label Levosalbutamol, Interaksi obat)

  • Lidokain dan epinefrinanestetik lokalModerat

    When involvement of the tongue, glottis, or larynx appears likely to cause airway obstruction, appropriate therapy, e.g., subcutaneous epinephrine injection 1:1000 (0.3 - 0.5 mL) should be promptly administered ( see PRECAUTIONS and ADVERSE REACTIONS ). (label Benazepril dan hidroklorotiazid, Peringatan)

  • Linagliptinpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Linagliptin dan metforminpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • LinezolidantibiotikModerat

    Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (label Linezolid, Peringatan dan perhatian)

  • Liraglutidagonis reseptor GLP-1Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Litiumobat serotonergikModerat

    Lithium: Renal clearance of lithium is reduced by thiazides and increase the risk of lithium toxicity. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Lofeksidinagonis alfa-adrenergikModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • LumateperonantipsikotikModerat

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (label Lumateperon, Peringatan dan perhatian)

  • LurasidonantipsikotikModerat

    Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (label Lurasidon, Peringatan dan perhatian)

  • MekamilaminantihipertensiModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • MeklizinantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MeloksikamOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MetadonopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Metaksalonpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MetforminbiguanidModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MetildopaantihipertensiModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Metilfenidatstimulan SSPModerat

    Antihypertensive Drugs: Monitor blood pressure. (label Metilfenidat, Interaksi obat)

  • MetoheksitalbarbituratModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Metokarbamolpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Metoprololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • MetotreksatimunosupresanModerat

    Antineoplastic agents (e.g., cyclophosphamide, methotrexate) : Concomitant use of thiazide diuretics may reduce renal excretion of cytotoxic agents and enhance their myelosuppressive effects. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MetskopolaminantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MiglitolantidiabetesModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • MilnasipranSNRIModerat

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (label Milnasipran, Peringatan dan perhatian)

  • MirtazapinantidepresanModerat

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (label Mirtazapin, Peringatan dan perhatian)

  • Modafinilstimulan SSPModerat

    However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (label Modafinil, Peringatan dan perhatian)

  • MorfinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NabumetonOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Nadololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Nafsilinantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • NalbufinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NaproksenOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NateglinidmeglitinidModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (label Natrium zirkonium siklosilikat, Peringatan dan perhatian)

  • Nebivololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • NiasinModerat

    Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (label Niasin, Interaksi obat)

  • Nifedipinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Nikardipinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Nimodipinpenghambat kanal kalsium dihidropiridinModerat

    Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (label Nimodipin, Interaksi obat)

  • Nisoldipinpenghambat kanal kalsium dihidropiridinModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • NitrogliserinnitratModerat

    Antihypertensives: Possible additive hypotensive effects. (label Nitrogliserin, Interaksi obat)

  • NitroprusidvasodilatorModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Nortriptilinantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • OksaprozinOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Oksasilinantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • OksibutininantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • OksikodonopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • OksimorfonopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • OlanzapinantipsikotikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Olanzapin dan fluoksetinantipsikotikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • OliseridinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Omeprazolpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (label Omeprazol, Peringatan dan perhatian)

  • Omeprazol dan natrium bikarbonatpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (label Omeprazol dan natrium bikarbonat, Peringatan dan perhatian)

  • Orfenadrinpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • PaliperidonantipsikotikModerat

    Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (label Paliperidon, Peringatan dan perhatian)

  • Pantoprazolpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (label Pantoprazol, Peringatan dan perhatian)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Parikalsitolanalog vitamin DModerat

    The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (label Parikalsitol, Peringatan dan perhatian)

  • ParoksetinSSRIModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • PazopanibModerat

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (label Pazopanib, Peringatan dan perhatian)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • PentoksifilinmetilxantinModerat

    Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (label Pentoksifilin, Interaksi obat)

  • PetidinopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Pindololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • PioglitazontiazolidindionModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Pioglitazon dan glimepiridtiazolidindionModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Pioglitazon dan metformintiazolidindionModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Piperasilin dan tazobaktamantibiotik penisilinModerat

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (label Benazepril dan hidroklorotiazid, Peringatan)

  • PiroksikamOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Prazosinpenyekat alfaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • PregabalinantikonvulsanModerat

    In addition, patients who are taking other drugs associated with angioedema (e.g., angiotensin converting enzyme inhibitors [ACE-inhibitors]) may be at increased risk of developing angioedema. (label Pregabalin, Peringatan dan perhatian)

  • Prilokain dan epinefrinanestetik lokalModerat

    When involvement of the tongue, glottis, or larynx appears likely to cause airway obstruction, appropriate therapy, e.g., subcutaneous epinephrine injection 1:1000 (0.3 - 0.5 mL) should be promptly administered ( see PRECAUTIONS and ADVERSE REACTIONS ). (label Benazepril dan hidroklorotiazid, Peringatan)

  • PrimidonantikonvulsanModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • ProklorperazinantipsikotikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • PrometazinantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Propranololpenyekat betaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Protriptilinantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Rabeprazolpenghambat pompa protonModerat

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (label Rabeprazol, Peringatan dan perhatian)

  • RemifentanilopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • RepaglinidmeglitinidModerat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • RiosiguatvasodilatorModerat

    Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (label Riosiguat, Peringatan dan perhatian)

  • RisperidonantipsikotikModerat

    Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (label Risperidon, Peringatan dan perhatian)

  • Saksagliptinpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Saksagliptin dan metforminpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Salbutamolagonis beta-adrenergikModerat

    Diuretics: Use with caution. (label Salbutamol, Interaksi obat)

  • Salmeterolagonis beta-adrenergikModerat

    • Diuretics: Use with caution. (label Salmeterol, Interaksi obat)

  • SalsalatOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SefepimsefalosporinModerat

    Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (label Sefepim, Interaksi obat)

  • SeftazidimsefalosporinModerat

    Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (label Seftazidim, Interaksi obat)

  • SelekoksibOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Semaglutidagonis reseptor GLP-1Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SertralinSSRIModerat

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (label Sertralin, Peringatan dan perhatian)

  • Siklobenzaprinpelemas ototModerat

    Digitalis glycosides: Thiazide-induced hypokalemia or hypomagnesemia may predispose the patients to digoxin toxicity Skeletal muscle relaxants: Possible increased responsiveness to muscle relaxants such as curare derivatives. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SiklofosfamidimunosupresanModerat

    Antineoplastic agents (e.g., cyclophosphamide, methotrexate) : Concomitant use of thiazide diuretics may reduce renal excretion of cytotoxic agents and enhance their myelosuppressive effects. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SiklopentolatantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Sildenafilpenghambat PDE5Moderat

    Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (label Sildenafil, Peringatan dan perhatian)

  • Silodosinpenyekat alfaModerat

    However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (label Silodosin, Peringatan dan perhatian)

  • SiproheptadinantihistaminModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SirolimusimunosupresanModerat

    Patients receiving coadministration of ACE inhibitor and mTOR (mammalian target of rapamycin) inhibitor (e.g., tesmsirolimus, sirolimus, everolimus) therapy or a neprilysin inhibitor may be at increased risk for angioedema (see PRECAUTIONS ) . (label Benazepril dan hidroklorotiazid, Peringatan)

  • Sitagliptinpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Sitagliptin dan metforminpenghambat DPP-4Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SitalopramSSRIModerat

    Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (label Sitalopram, Peringatan dan perhatian)

  • SkopolaminantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SolifenasinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SorafenibModerat

    Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (label Sorafenib, Peringatan dan perhatian)

  • Sotalolpenyekat betaModerat

    Other ACE inhibitors have had less than additive effects with beta-adrenergic blockers, presumably because drugs of both classes lower blood pressure by inhibiting parts of the renin-angiotensin system. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Spironolaktonantagonis aldosteronModerat

    Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Suksinilkolinpenyekat neuromuskularModerat

    Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (label Suksinilkolin, Peringatan dan perhatian)

  • SulindakOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SunitinibModerat

    Initiate and/or adjust antihypertensive therapy as appropriate. (label Sunitinib, Peringatan dan perhatian)

  • TakrolimusimunosupresanModerat

    • Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (label Takrolimus, Peringatan dan perhatian)

  • TapentadolopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Monitor potassium periodically. mTOR (mammalian target of rapamycin) inhibitor s : Patients receiving coadministration of ACE inhibitor and mTOR inhibitor (e.g., temsirolimus, sirolimus, everolimus) therapy may be at increased risk for angioedema ( see WARNINGS ). (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Terazosinpenyekat alfaModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Terbutalinagonis beta-adrenergikModerat

    Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (label Terbutalin, Perhatian)

  • TestosteronandrogenModerat

    In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (label Testosteron, Peringatan dan perhatian)

  • Timololpenyekat betaModerat

    Other ACE inhibitors have had less than additive effects with beta-adrenergic blockers, presumably because drugs of both classes lower blood pressure by inhibiting parts of the renin-angiotensin system. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TioridazinantipsikotikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TiotropiumantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Tirzepatidagonis reseptor GLP-1Moderat

    Antidiabetic agents: Dosage adjustment of antidiabetic drug may be required. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Tizanidinpelemas ototModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • TobramisinaminoglikosidaModerat

    Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (label Tobramisin, Interaksi obat)

  • TolmetinOAINSModerat

    NSAIDs and Cox-2 selective agents: In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including benazepril, may result in deterioration of renal function, including possible acute renal failure. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TolterodinantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TolvaptanModerat

    Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (label Tolvaptan, Peringatan dan perhatian)

  • TopiramatantikonvulsanModerat

    Hydrochlorothiazide (HCTZ) Topiramate C max and AUC increased when HCTZ was added to immediate-release topiramate. (label Topiramat, Interaksi obat)

  • Torasemiddiuretik loopModerat

    Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (label Benazepril dan hidroklorotiazid, Peringatan)

  • Toremifenmodulator reseptor estrogen selektifModerat

    Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (label Toremifen, Interaksi obat)

  • TramadolopioidModerat

    Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Alcohol, barbiturates or narcotics: Concomitant administration of thiazide diuretics with alcohol, barbiturates, or narcotics may potentiate orthostatic hypotension. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TrazodonantidepresanModerat

    Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (label Trazodon, Peringatan dan perhatian)

  • Triamterendiuretik hemat kaliumModerat

    Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (label Benazepril dan hidroklorotiazid, Peringatan)

  • TrifluoperazinantipsikotikModerat

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (label Trifluoperazin, Perhatian)

  • TriheksifenidilantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Trimipraminantidepresan trisiklikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TrospiumantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • UmeklidiniumantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Umeklidinium dan vilanterolantikolinergikModerat

    Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Vardenafilpenghambat PDE5Moderat

    Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (label Vardenafil, Interaksi obat)

  • VenlafaksinSNRIModerat

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (label Venlafaksin, Peringatan dan perhatian)

  • Verapamilpenghambat kanal kalsiumModerat

    The thiazide component of Lotensin HCT may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (label Benazepril dan hidroklorotiazid, Peringatan)

  • VilazodonSSRIModerat

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (label Vilazodon, Peringatan dan perhatian)

  • Vitamin DVitamin dan mineralModerat

    Diuretik tiazid mengurangi ekskresi kalsium; bila dikombinasikan dengan suplemen vitamin D dan kalsium, hal ini dapat berujung pada hiperkalsemia, terutama pada orang lanjut usia. (NIH Office of Dietary Supplements, Vitamin D)

  • VortioksetinantidepresanModerat

    Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (label Vortioksetin, Peringatan dan perhatian)

  • ZiprasidonantipsikotikModerat

    Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (label Ziprasidon, Peringatan dan perhatian)

Penyebutan minor (44)

  • Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (label Ambrisentan, Peringatan dan perhatian)

  • ApiksabanantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • ArgatrobanantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • AzatioprinimunosupresanMinor

    Use with Angiotensin-Converting Enzyme Inhibitors: The use of angiotensin-converting enzyme inhibitors to control hypertension in patients on azathioprine has been reported to induce anemia and severe leukopenia. (label Azatioprin, Interaksi obat)

  • BivalirudinantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Bosentanpenginduksi CYP3A4Minor

    Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (label Bosentan, Peringatan dan perhatian)

  • DabigatranantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Dalfampridinsuplemen kaliumMinor

    Interactions Common for Both Benazepril and Hydrochlorothiazide Potassium Supplements and Potassium -Sparing Diuretics: Concomitant use with Lotensin HCT may effect potassium levels. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (label Dasatinib, Peringatan dan perhatian)

  • Dekstroamfetaminstimulan SSPMinor

    Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (label Dekstroamfetamin, Interaksi obat)

  • Desogestrel dan etinilestradiolkontrasepsi oralMinor

    If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (label Desogestrel dan etinilestradiol, Peringatan)

  • Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (label Dosetaksel, Peringatan dan perhatian)

  • DronedaronantiaritmiaMinor

    Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (label Dronedaron, Peringatan dan perhatian)

  • EdoksabanantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • EfedrinsimpatomimetikMinor

    Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (label Efedrin, Interaksi obat)

  • EnoksaparinantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • In addition to discontinuation of the drug, diuretic therapy may be required. (label Estrogen teresterifikasi dan metiltestosteron, Peringatan)

  • Febuksostatpenghambat xantin oksidaseMinor

    In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, ULORIC does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology (12.3) ]. (label Febuksostat, Interaksi obat)

  • Finasteridpenghambat 5-alfa reduktaseMinor

    …specific interaction studies were not performed, PROSCAR was concomitantly used in clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory… (label Finasterid, Interaksi obat)

  • FlekainidantiaritmiaMinor

    Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (label Flekainid, Interaksi obat)

  • FondaparinuksantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • HeparinantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (label Ikatibant, Interaksi obat)

  • Imatinibpenghambat CYP3A4Minor

    Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (label Imatinib, Peringatan dan perhatian)

  • Kalium kloridasuplemen kaliumMinor

    Interactions Common for Both Benazepril and Hydrochlorothiazide Potassium Supplements and Potassium -Sparing Diuretics: Concomitant use with Lotensin HCT may effect potassium levels. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • KalsiumVitamin dan mineralMinor

    Diuretik tiazid mengurangi ekskresi kalsium, sehingga asupan kalsium yang tinggi dapat menaikkan kalsium darah. (NIH Office of Dietary Supplements, Calcium)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (label Kalsium glukonat, Interaksi obat)

  • Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (label Kortikotropin, Interaksi obat)

  • MagnesiumVitamin dan mineralMinor

    Penggunaan jangka panjang diuretik loop dan diuretik tiazid meningkatkan kehilangan magnesium melalui urine. (NIH Office of Dietary Supplements, Magnesium)

  • Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (label Masitentan, Peringatan dan perhatian)

  • MeksiletinantiaritmiaMinor

    In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (label Meksiletin, Interaksi obat)

  • MetilprednisolonkortikosteroidMinor

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (label Metilprednisolon, Interaksi obat)

  • MetiltestosteronandrogenMinor

    In addition to discontinuation of the drug, diuretic therapy may be required. (label Metiltestosteron, Peringatan)

  • Milrinonpenghambat PDE3Minor

    …been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (label Milrinon, Interaksi obat)

  • Natrium polistiren sulfonatsuplemen kaliumMinor

    Interactions Common for Both Benazepril and Hydrochlorothiazide Potassium Supplements and Potassium -Sparing Diuretics: Concomitant use with Lotensin HCT may effect potassium levels. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • PrednisolonkortikosteroidMinor

    Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (label Prednisolon, Interaksi obat)

  • PrednisonkortikosteroidMinor

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (label Prednison, Interaksi obat)

  • RivaroksabanantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • SidofovirantivirusMinor

    Drug Interactions Probenecid Probenecid is known to interact with the metabolism or renal tubular excretion of many drugs (e.g., acetaminophen, acyclovir, angiotensin-converting enzyme inhibitors, aminosalicylic acid, barbiturates, benzodiazepines, bumetanide, clofibrate, methotrexate, famotidine, furosemide, nonsteroidal anti-inflammatory agents, theophylline,… (label Sidofovir, Interaksi obat)

  • Simetidinpenghambat H2Minor

    Benazepril Benazepril has been used concomitantly with beta-adrenergic-blocking agents, calcium-blocking agents, cimetidine, diuretics, digoxin, hydralazine, and naproxen without evidence of clinically important adverse interactions. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • TerbinafinantijamurMinor

    There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (label Terbinafin, Interaksi obat)

  • TriamsinolonkortikosteroidMinor

    Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (label Triamsinolon, Interaksi obat)

  • WarfarinantikoagulanMinor

    Interaction studies with warfarin and acenocoumarol have failed to identify any clinically important effects of benazepril on the serum concentrations or clinical effects of these anticoagulants. (label Benazepril dan hidroklorotiazid, Interaksi obat)

  • Zink (seng)Vitamin dan mineralMinor

    Diuretik tiazid meningkatkan kehilangan zink melalui urine pada penggunaan jangka panjang. (NIH Office of Dietary Supplements, Zinc)

Tidak ada interaksi bermakna yang dilaporkan (2)

  • PamidronatbisfosfonatTanpa interaksi

    Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (label Pamidronat, Interaksi obat)

  • Ropinirolagonis dopaminTanpa interaksi

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (label Ropinirol, Interaksi obat)

Periksa Benazepril dan hidroklorotiazid terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.