Alendronate and Calcium interaction
Alendronate and Calcium: the Alendronate prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
Curated guidance for Calcium
Calcium binds these drugs in the gut and can sharply cut how much is absorbed; separate the doses.
From the Alendronate (Binosto) label · effective 2026-02-06
Calcium supplements, antacids or oral medications containing multivalent cations interfere with absorption of alendronate.
Calcium Supplements/Antacids Co-administration of BINOSTO and calcium, antacids, or oral medications containing multivalent cations will interfere with absorption of BINOSTO.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.