Aliskiren and Bupivacaine and epinephrine interaction

Aliskiren and Bupivacaine and epinephrine: the Aliskiren prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Aliskiren (Tekturna) label · effective 2024-03-07

Minor

Prompt administration of subcutaneous epinephrine solution 1:1000 (0.3 mL to 0.5 mL) and measures to ensure a patent airway may be necessary.

Warnings and precautionsnames Bupivacaine and epinephrineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.