Aliskiren and Mecamylamine interaction

Aliskiren and Mecamylamine: the Mecamylamine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Mecamylamine (Vecamyl) label · effective 2025-02-20

Moderate

The action of Mecamylamine HCl may be potentiated by anesthesia, other antihypertensive drugs and alcohol.

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Minor

When ganglion blockers or other potent antihypertensive drugs are discontinued suddenly, hypertensive levels return.

Warningsby drug classView label on DailyMed
Minor

When Mecamylamine HCl is withdrawn, this should be done gradually and other antihypertensive therapy usually must be substituted.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.