Amlodipine and Carvedilol interaction

Amlodipine and Carvedilol: the Carvedilol prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Carvedilol (Coreg) label · effective 2026-07-31

Moderate

COREG may be used with caution, however, in patients who do not respond to, or cannot tolerate, other antihypertensive agents.

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Moderate

As with other β-blockers, if COREG is administered with calcium channel blockers of the verapamil or diltiazem type, it is recommended that ECG and blood pressure be monitored.

Drug interactionsby drug classView label on DailyMed
Minor

Verapamil- or diltiazem-type calcium channel blockers may affect ECG and/or blood pressure.

Drug interactionsby drug classView label on DailyMed
Minor

Calcium Channel Blockers Conduction disturbance (rarely with hemodynamic compromise) has been observed when COREG is coadministered with diltiazem.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.