Amoxicillin and clavulanate and Medroxyprogesterone interaction
Amoxicillin and clavulanate and Medroxyprogesterone: the Amoxicillin and clavulanate prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Amoxicillin and clavulanate (Amoxicillin and Clavulanate Potassium) label · effective 2026-07-07
Amoxicillin and Clavulanate Potassium Extended Release Tablets may reduce efficacy of oral contraceptives.
Oral Contraceptives Amoxicillin and Clavulanate Potassium Extended Release Tablets may affect intestinal flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.