Ampicillin and Chloroquine interaction

Ampicillin and Chloroquine: the Chloroquine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Chloroquine (Chloroquine Phosphate) label · effective 2026-01-13

Moderate

Ampicillin: In a study of healthy volunteers, chloroquine significantly reduced the bioavailability of ampicillin.

Drug interactionsnames AmpicillinView label on DailyMed
Minor

An interval of at least two hours between intake of ampicillin and chloroquine should be observed.

Drug interactionsnames AmpicillinView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.