Ampicillin and Hydroxychloroquine interaction
Ampicillin and Hydroxychloroquine: the Hydroxychloroquine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Hydroxychloroquine (Plaquenil) label · effective 2026-04-09
Ampicillin In a study of healthy volunteers, chloroquine significantly reduced the bioavailability of ampicillin.
Interaction of ampicillin with hydroxychloroquine cannot be ruled out.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.