Antacids (Tums, Maalox, Mylanta) and Etodolac interaction

Antacids (Tums, Maalox, Mylanta) and Etodolac: the Etodolac prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Etodolac label · effective 2026-01-29

Moderate

However, antacids can decrease the peak concentration reached by 15% to 20% but have no detectable effect on the time-to-peak.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed
Minor

Antacids The concomitant administration of antacids has no apparent effect on the extent of absorption of etodolac tablets.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.