Antacids (Tums, Maalox, Mylanta) and Hydroxychloroquine interaction
Antacids (Tums, Maalox, Mylanta) and Hydroxychloroquine: the Hydroxychloroquine prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Hydroxychloroquine (Plaquenil) label · effective 2026-04-09
Antacids and kaolin Antacids and kaolin can reduce absorption of chloroquine; an interval of at least 4 hours between intake of these agents and chloroquine should be observed.
Interaction of antacids and kaolin with hydroxychloroquine cannot be ruled out.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.