Antacids (Tums, Maalox, Mylanta) and Quinine interaction

Antacids (Tums, Maalox, Mylanta) and Quinine: the Quinine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Quinine (QUININE SULFATE) label · effective 2025-10-31

Major

Concomitant administration of these antacids with quinine sulfate should be avoided.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed
Moderate

Antacids Antacids containing aluminum and/or magnesium may delay or decrease absorption of quinine.

Drug interactionsnames Antacids (Tums, Maalox, Mylanta)View label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.