Benzphetamine and Labetalol interaction

Benzphetamine and Labetalol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Benzphetamine (Benzphetamine Hydrochloride) label · effective 2026-06-18

Moderate

Amphetamines may decrease the hypotensive effect of antihypertensives.

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From the Labetalol (Labetalol Hydrochloride) label · effective 2025-12-19

Minor

Labetalol has also been reported to produce a false-positive test for amphetamine when screening urine for the presence of drugs using the commercially available assay methods.

Drug interactionsby drug classView label on DailyMed
Minor

When patients being treated with labetalol have a positive urine test for amphetamine using these techniques, confirm using more specific methods, such as a gas chromatographic-mass spectrometer technique.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.