Benzphetamine and Phendimetrazine interaction

Benzphetamine and Phendimetrazine: both prescribing labels flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Phendimetrazine (PHENDIMETRAZINE TARTRATE) label · effective 2025-12-19

Major

…hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy (see PRECAUTIONS, Pregnancy ) • Nursing • Use in combination with other anorectic agents or CNS stimulants • Known hypersensitivity or idiosyncratic reactions to sympathomimetics

Contraindicationsby drug classView label on DailyMed

From the Benzphetamine (Benzphetamine Hydrochloride) label · effective 2026-06-18

Major

Benzphetamine Hydrochloride Tablets should not be used concomitantly with other CNS stimulants.

Contraindicationsby drug classView label on DailyMed
Major

Benzphetamine hydrochloride tablets should not be used concomitantly with other CNS stimulants.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.