Bisoprolol and hydrochlorothiazide and Ipratropium and albuterol interaction

Bisoprolol and hydrochlorothiazide and Ipratropium and albuterol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Ipratropium and albuterol (Ipratropium Bromide and Albuterol Sulfate) label · effective 2026-05-22

Moderate

Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded.

Drug interactionsby drug classView label on DailyMed
Moderate

Although the clinical significance of these effects is not known, caution is advised in the coadministration of β-agonist-containing drugs, such as Ipratropium Bromide and Albuterol Sulfate Inhalation Solution, with non-potassium sparing diuretics.

Drug interactionsby drug classView label on DailyMed

From the Bisoprolol and hydrochlorothiazide (bisoprolol fumarate and hydrochlorothiazide) label · effective 2026-08-11

Minor

A beta 2 agonist (bronchodilator) should be made available.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.