Bisoprolol and hydrochlorothiazide and Sotalol interaction
Bisoprolol and hydrochlorothiazide and Sotalol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Bisoprolol and hydrochlorothiazide (bisoprolol fumarate and hydrochlorothiazide) label · effective 2026-08-11
Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently.
Bisoprolol fumarate and hydrochlorothiazide tablets should not be combined with other beta-blocking agents.
From the Sotalol (Sotalol hydrochloride) label · effective 2025-07-31
Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.