Calcium and Ibandronate interaction

Calcium and Ibandronate: the Ibandronate prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Ibandronate (IBANDRONATE SODIUM) label · effective 2026-02-19

Moderate

Instruct patients to take supplemental calcium and vitamin D if their dietary intake is inadequate (see Dosage and Administration [2.3] ) .

Warnings and precautionsnames CalciumView label on DailyMed
Minor

Calcium supplements, antacids and some oral medications may interfere with absorption of ibandronate.

Drug interactionsnames CalciumView label on DailyMed
Minor

Calcium Supplements/Antacids Products containing calcium and other multivalent cations (such as aluminum, magnesium, iron) are likely to interfere with absorption of ibandronate sodium tablets.

Drug interactionsnames CalciumView label on DailyMed

Curated guidance for Calcium

Moderate

Calcium binds these drugs in the gut and can sharply cut how much is absorbed; separate the doses.

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.