Carbamazepine and Cisatracurium interaction
Carbamazepine and Cisatracurium: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Cisatracurium (Cisatracurium Besylate) label · effective 2026-06-30
Antibiotics † Local anesthetics Magnesium salts Procainamide Lithium Quinidine May prolong the neuromuscular blockade action of Cisatracurium Besylate Injection Phenytoin, Carbamazepine May increase resistance to the neuromuscular blockade action of Cisatracurium Besylate Injection resulting in shorter durations of neuromuscular blockade and infusion rate requirements…
Resistance to Neuromuscular Blockade with Certain Drugs Shorter durations of neuromuscular block may occur and Cisatracurium Besylate Injection infusion rate requirements may be higher in patients chronically administered phenytoin or carbamazepine [see Drug Interactions ( 7.1 ) and Clinical Pharmacology ( 12.3 )] .
Phenytoin and Carbamazepine : May shorten duration of neuromuscular blockade.
From the Carbamazepine (EQUETRO) label · effective 2025-08-19
N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.