Carbamazepine and Irbesartan and hydrochlorothiazide interaction
Carbamazepine and Irbesartan and hydrochlorothiazide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Carbamazepine (EQUETRO) label · effective 2025-08-19
Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia.
From the Irbesartan and hydrochlorothiazide (Avalide) label · effective 2025-10-07
Carbamazepine: Increased risk of hyponatremia.
Carbamazepine Concomitant use of carbamazepine and hydrochlorothiazide has been associated with the risk of symptomatic hyponatremia.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.