Carvedilol and Labetalol interaction

Carvedilol and Labetalol: the Carvedilol prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Carvedilol (Coreg) label · effective 2026-07-31

Moderate

COREG may be used with caution, however, in patients who do not respond to, or cannot tolerate, other antihypertensive agents.

Warnings and precautionsby drug classView label on DailyMed
Moderate

As with other β-blockers, if COREG is administered with calcium channel blockers of the verapamil or diltiazem type, it is recommended that ECG and blood pressure be monitored.

Drug interactionsby drug classView label on DailyMed
Minor

As with other β-blockers, when discontinuation of COREG is planned, the patients should be carefully observed and advised to limit physical activity to a minimum.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.