Chenodiol and Warfarin interaction
Chenodiol and Warfarin: the Chenodiol prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.
Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.
What the FDA labels say
From the Chenodiol (CTEXLI) label · effective 2025-12-16
If concomitant use of CTEXLI with coumarin or its derivatives is unavoidable, monitor prothrombin time.
• Coumarin and its derivatives: Monitor prothrombin time and adjust dosage accordingly.
Effect of CTEXLI on Other Drugs Due to potential hepatotoxicity, CTEXLI may affect the pharmacodynamics of coumarin and its derivatives, causing unexpected prolongation of the prothrombin time and hemorrhage.
Adjust the dosage of coumarin or its derivatives in accordance with its approved product labeling.
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Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.