Antacids (Tums, Maalox, Mylanta) and Chenodiol interaction
Antacids (Tums, Maalox, Mylanta) and Chenodiol: the Chenodiol prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.
Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.
What the FDA labels say
From the Chenodiol (CTEXLI) label · effective 2025-12-16
• Bile acid sequestering agents and aluminum-based antacids: Avoid concomitant use with CTEXLI.
Avoid concomitant use of bile acid sequestering agents or aluminum-based antacids with CTEXLI.
Effect of Other Drugs on CTEXLI Co-administration of bile acid sequestering agents, such as cholestyramine and colestipol, or aluminum-based antacids may decrease absorption of CTEXLI in the intestine and may result in decreased efficacy of CTEXLI.
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Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.