Clonidine and Sorafenib interaction
Clonidine and Sorafenib: the Sorafenib prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Sorafenib (Nexavar) label · effective 2023-08-28
Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy.
In cases of severe or persistent hypertension despite institution of antihypertensive therapy, consider temporary or permanent discontinuation of NEXAVAR [see Dosage and Administration ( 2.2 )] .
Hypertension was usually mild to moderate, occurred early in the course of treatment, and was managed with standard antihypertensive therapy.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.