Corticotropin and Triamterene and hydrochlorothiazide interaction

Corticotropin and Triamterene and hydrochlorothiazide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Triamterene and hydrochlorothiazide label · effective 2026-07-16

Moderate

Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect.

Drug interactionsnames CorticotropinView label on DailyMed

From the Corticotropin (Acthar) label · effective 2026-07-15

Minor

Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy.

Drug interactionsby drug classView label on DailyMed
Minor

Acthar Gel may accentuate electrolyte loss associated with diuretics.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.