Cyclophosphamide and Warfarin interaction

Cyclophosphamide and Warfarin: the Cyclophosphamide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Cyclophosphamide (Frindovyx) label · effective 2026-08-26

Moderate

Coumarins Both increased and decreased warfarin effect have been reported in patients receiving warfarin and cyclophosphamide.

Drug interactionsnames WarfarinView label on DailyMed
Moderate

Monitor anticoagulant activity closely in patients receiving warfarin or other coumarins.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.