Cysteamine and Penicillamine interaction

Cysteamine and Penicillamine: the Cysteamine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Cysteamine (PROCYSBI) label · effective 2026-06-25

Major

The use of PROCYSBI is contraindicated in patients with a serious hypersensitivity reaction, including anaphylaxis, to penicillamine or cysteamine.

Contraindicationsnames PenicillamineView label on DailyMed
Major

Hypersensitivity to penicillamine or cysteamine ( 4 )

Contraindicationsnames PenicillamineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.