Daunorubicin and Methotrexate interaction

Daunorubicin and Methotrexate: the Daunorubicin prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Daunorubicin (Daunorubicin Hydrochloride) label · effective 2024-02-15

Moderate

Hepatotoxic medications, such as high-dose methotrexate, may impair liver function and increase the risk of toxicity.

Drug interactionsnames MethotrexateView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.