Digoxin and Ibutilide interaction
Digoxin and Ibutilide: the Ibutilide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Ibutilide (Corvert) label · effective 2024-01-25
Digoxin: Supraventricular arrhythmias may mask the cardiotoxicity associated with excessive digoxin levels.
Therefore, it is advisable to be particularly cautious in patients whose plasma digoxin levels are above or suspected to be above the usual therapeutic range.
WARNINGS Proarrhythmia: Like other antiarrhythmic agents, CORVERT Injection can induce or worsen ventricular arrhythmias in some patients.
Coadministration of digoxin did not have effects on either the safety or efficacy of ibutilide in the clinical trials.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.